Welcome
To the laboratory of Dr. Caroline E. Bass laboratory in the Department of Pharmacology and Toxicology at the Jacobs School of Medicine and Biomedical Sciences of the University at Buffalo, SUNY.
The goal of our lab is to understand the fundamental changes in brain circuits caused by drugs of abuse, in order to develop better treatments for addiction. We use optogenetics and chemogenetics to manipulate neural circuits in rat models of reward seeking and taking behaviors. We specialize in designing viral vectors and combinatorial viral strategies to target neuronal subtypes and subtype specific projections in wild type animals. We apply these viral manipulations to rat models of behaviors, including i.v. drug, alcohol and food self-administration, as well as other sophisticated operant models.
We recently moved our lab to the new Jacobs School of Medicine and Biomedical Sciences building in downtown Buffalo, located in the heart of the Buffalo Niagara Medical Campus. This move aligns us with a wealth of resources including the Research Institutes on Addiction, Buffalo General Medical Center, the John R. Oishei Children’s Hospital, and Roswell Park Comprehensive Cancer Center.
Find out more about us, our research, resources we provide and opportunities in the lab using the tabs above.
The goal of our lab is to understand the fundamental changes in brain circuits caused by drugs of abuse, in order to develop better treatments for addiction. We use optogenetics and chemogenetics to manipulate neural circuits in rat models of reward seeking and taking behaviors. We specialize in designing viral vectors and combinatorial viral strategies to target neuronal subtypes and subtype specific projections in wild type animals. We apply these viral manipulations to rat models of behaviors, including i.v. drug, alcohol and food self-administration, as well as other sophisticated operant models.
We recently moved our lab to the new Jacobs School of Medicine and Biomedical Sciences building in downtown Buffalo, located in the heart of the Buffalo Niagara Medical Campus. This move aligns us with a wealth of resources including the Research Institutes on Addiction, Buffalo General Medical Center, the John R. Oishei Children’s Hospital, and Roswell Park Comprehensive Cancer Center.
Find out more about us, our research, resources we provide and opportunities in the lab using the tabs above.